Project SAFE (Secure Analytics for Future Emergencies) is a collaboration among city agencies, hospitals, universities, and community organizations, developed in partnership with the Mayor’s Office of Performance and Innovation (OPI) and the Baltimore Neighborhood Indicators Alliance (BNIA). The project strengthens how Baltimore prepares for and responds to emergencies such as pandemics, extreme weather, and public safety incidents by building a secure, federated data and analytics framework that supports trusted, equitable collaboration. Through privacy-preserving technologies, real-time forecasting, and transparent governance, SAFE enables coordinated data use without compromising confidentiality. The initiative will create predictive dashboards for health, safety, and environmental resilience, formalize data-sharing agreements, and involve residents in shaping safeguards and priorities. By 2028, Project SAFE aims to establish a citywide system that enhances coordination, trust, and equity in crisis response, positioning Baltimore as a regional model for data-driven resilience.